OK; let's do this:
Search your system for a file labeled "lsb.ini." You will find two of them. (To find the second one, you may have to search hidden files and folders.)
One of them will be in this folder:
C:\Documents and Settings\All Users\Application Data\Concordia Publishing House\Lutheran Service Builder 2\
We'd like to rename that file to something else.
The next time you start Builder, it will recreate that file from scratch. You will have to re-point Builder in the direction of your SQL databases for Builder (if you need help with this, just let me know). You will then have to activate Builder one more time.
After this activation, you should not see the activation prompt again. If you do, please let me know and we'll take some additional steps to solve the problem.